Protein Synthesis - Biological Central Dogma
Sabtu, 09 November 2013
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Protein synthesis, Protein synthesis is a process to synthesize
amino acid in polynucleotide chain. Information encoded in genes determines the
final expression of amino acid sequence
in polynucleotide.
Biological Central
Dogma
The
correlation between DNA and RNA in heredity, cell structure, and Cell
activities are summarized in central dogma concept. The concept can be
interpreted as "the source of all information" ' It can be noted in the Following scheme.
The scheme of central dogma
|
The concept
above explains that
the primary key in protein synthesis is DNA, the genetic material of a cell. The arrow
directing leftward means that the DNA is
able to reproduce itself
through replication. The Arrow
directing rightward means that
the DNA is able to monitor RNA Synthesis
(through transcription process) and protein synthesis (through translation process).
Protein
synthesis involves transcription and
translation
processes.
|
DNA
replication occurs in the cell nucleus
when preparing mitosis and meiosis divisions. Without replication,
the daughter cell will not obtain
any information required
to continue its life. The result of transcription process is the information of dRNA strand which is
the copy of DNA strand.
Source. Biology. Concepts & Con nections, 2006.
Sulforhodamine B (SRB) Cell Cytotoxicity Assay Sulforhodamine B (SRB) cell cytotoxicity assay has been widely used for drug toxicity screening and cell proliferation detection.
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