2013 The Components Of Immune System Are macrophage, Lymphocyte And Antigen Receptor
Rabu, 17 April 2013
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1. Macrophage
Macrophage
is the white blood cell component which has the function of innate immunity
through phagocytosis process. Before digesting the bacteria, macrophage tries
to reach the bacteria and capture it with membrane extension called
pseudopodia. After the bacteria is enveloped within the membrane, macrophage
will ingest the bacteria one by one and then digest it.
To
overcome infection, sometimes macrophage interacts with lymphocyte. For
example, macrophage interacts with lymphocyte to fight bacteria Stretococcus pygenes.
Macrophage
also plays a vital role in adaptive immunity that is by sending antigen to be
destroyed by other components of adaptive immune system. Microphage is able to
digest foreign particles, such as dust, asbestos particles, and bacteria.
Macrophage can be found in strategic site of the body and in the organ related
to blood circulation or outside environment, for example in lungs which receive
air from the outside.
Lymphocyte
is the white blood cell that has specific function to identify and destroy
invader antigen. All lymphocytes are formed in bone marrow, but they get mature
in two different sites. The lymphocyte that is mature in bone marrow is called
B lymphocyte or B cell. It produces antibody which circulates through blood and
other body’s fluid.
The T lymphocyte or T cell is mature in thymus. T
Lymphocyte is also called cytotoxic (poisonous cell) or killer T lymphocyte. The T cell kill directly all the cell having
specific antigen on it is surface which has been recognized by T cells. The
helper T lymphocyte controls the strength and quality of all immune responds.
Mature lymphocyte cell flow constantly in blood toward thymus gland and back
into the blood to monitor the body from invader substances continuously.
3. Antigen Receptor
After
having maturation, every lymphocyte will make one receptor antigen with a
specific structure on the surface of lymphocyte cell. The structure will bind
the proper structure in antigen, just like a lock and its key.
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